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北京脑重大疾病省部共建国家重点实验室培育基地

所属学院:脑重大疾病研究中心(北京脑重大疾病研究院)

研究方向:脑血管病 阿尔茨海默病 帕金森病 脑肿瘤 癫痫 神经损伤与修复 抑郁症 精神分裂症。

团队成员:王拥军 贾建平 陈彪 王刚 李人 江涛 栾国明 李建军 

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191 条 记 录,以下是 1-30

高危非致残性缺血性脑血管事件诊疗指南被引量:122收藏 分享
作者:王伊龙[1] 赵性泉[1] 刘新峰[2] 曾进胜[3] 许予明[4]
机构:首都医科大学附属北京天坛医院;南京军区总医院;中山大学附属第一医院;郑州大学第一附属医院;第四军医大学西京医院
来源:《中国卒中杂志》  
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阿尔茨海默病发生机制的研究进展被引量:83收藏 分享
作者:张静爽[1] 王蓉[1]
机构:首都医科大学宣武医院中心实验室北京市老年病医疗研究中心北京脑重大疾病研究院阿尔茨海默病研究所神经变性病教育部重点实验室
来源:《首都医科大学学报》  
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cPKCγ-Modulated Autophagy in Neurons Alleviates Ischemic Injury in Brain of Mice with Ischemic Stroke Through Akt-mTOR Pathway被引量:51收藏 分享
作者:Wei H.[1] Li Y.[1] Han S.[1] Liu S.[1] Zhang N.[1]
机构:Department of Neurobiology and Center of Stroke;Department of Neurology
来源:Translational Stroke Research  
Age-related formaldehyde interferes with DNA methyltransferase function, causing memory loss in Alzheimer's disease被引量:50收藏 分享
作者:Tong, Zhiqian[1,2] Han, Chanshuai[1,3] Qiang, Min[1,3] Wang, Weishan[4] Lv, Jihui[4]
机构:Chinese Acad Sci;Capital Med Univ;Univ Chinese Acad Sci;Beijing Geriatr Hosp;Shantou Univ
来源:NEUROBIOLOGY OF AGING  
Mechanical thrombectomy and rescue therapy for intracranial large artery occlusion with underlying atherosclerosis被引量:49收藏 分享
作者:Jia, BaiXue[1] Feng, Lei[2] Liebeskind, David S.[3] Huo, Xiaochuan[1] Gao, Feng[1]
机构:Capital Med Univ;Kaiser Permanente Med Ctr;Univ Calif Los Angeles;Capital Med Univ;Beijing Inst Brain Disorders
来源:JOURNAL OF NEUROINTERVENTIONAL SURGERY  
alpha-Synuclein amino terminus regulates mitochondrial membrane permeability被引量:42收藏 分享
作者:Shen, Jiamei[1] Du, Tingting[1] Wang, Xue[1] Duan, Chunli[1] Gao, Ge[1]
机构:Capital Med Univ
来源:BRAIN RESEARCH  
Spinal cord injury repair by implantation of structured hyaluronic acid scaffold with PLGA microspheres in the rat被引量:35收藏 分享
作者:Wen, Yujun[1] Yu, Shukui[1] Wu, Yanhong[1] Ju, Rongkai[1] Wang, Hao[1]
机构:Capital Med Univ
来源:CELL AND TISSUE RESEARCH  
Clinical Utility and Lifespan Profiling of Neurological Soft Signs in Schizophrenia Spectrum Disorders被引量:30收藏 分享
作者:Chan, Raymond C. K.[1] Xie, Weizhen[2] Geng, Fu-lei[1,3] Wang, Ya[1] Lui, Simon S. Y.[1,3,4]
机构:Chinese Acad Sci;Univ Calif Riverside;Univ Chinese Acad Sci;Castle Peak Hosp;Capital Med Univ
来源:SCHIZOPHRENIA BULLETIN  
TGF-beta participates choroid neovascularization through Smad2/3-VEGF/TNF-alpha signaling in mice with Laser-induced wet age-related macular degeneration被引量:27收藏 分享
作者:Wang, Xiaolei[1,2,3] Ma, Wei[2,3,4] Han, Song[2,3] Meng, Zhaoyang[1] Zhao, Lu[1]
机构:Capital Med Univ;Capital Med Univ;Capital Med Univ;Capital Med Univ
来源:SCIENTIFIC REPORTS  
Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cells被引量:25收藏 分享
作者:Peng, Xiaohui[1] Zhou, Yan[1] Tian, Hua[1] Yang, Gaoxiang[1] Li, Chunliu[2]
机构:Capital Med Univ;Capital Med Univ;Capital Med Univ
来源:ONCOLOGY REPORTS  
Conversion of adult human peripheral blood mononuclear cells into induced neural stem cell by using episomal vectors被引量:21收藏 分享
作者:Tang, Xihe[1,2,3,4] Wang, Shuyan[1,2,3,4] Bai, Yunfei[5] Wu, Jianyu[1,2] Fu, Linlin[1,2]
机构:Capital Med Univ;Minist Educ;Beijing Inst Brain Disorders;Beijing Inst Brain Disorders;Capital Med Univ
来源:STEM CELL RESEARCH  
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells被引量:18收藏 分享
作者:Ling, Chen[1,2,3] Liu, Zunpeng[4,6] Song, Moshi[5,6,8] Zhang, Weiqi[1,3,6,8] Wang, Si[1,3,6,8]
机构:Capital Med Univ;Peking Univ;Chinese Acad Sci;Chinese Acad Sci;Chinese Acad Sci
来源:PROTEIN & CELL  
Sulforaphane metabolites cause apoptosis via microtubule disruption in cancer被引量:18收藏 分享
作者:Zhou, Yan[1] Yang, Gaoxiang[1] Tian, Hua[1] Hu, Yabin[1] Wu, Sai[1]
机构:Capital Med Univ;Capital Med Univ
来源:ENDOCRINE-RELATED CANCER  
The novel mechanism of rotenone-induced alpha-synuclein phosphorylation via reduced protein phosphatase 2A activity被引量:17收藏 分享
作者:Wang, Yi[1,2] Liu, Jia[1] Chen, Min[1] Du, Tingting[3,4] Duan, Chunli[1]
机构:Capital Med Univ;Capital Med Univ;Beijing Normal Univ;Beijing Normal Univ
来源:INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY  
Phenotype of postural instability/gait difficulty in Parkinson disease: relevance to cognitive impairment and mechanism relating pathological proteins and neurotransmitters被引量:17收藏 分享
作者:Zuo, Li-Jun[1] Piao, Ying-Shan[2] Li, Li-Xia[2] Yu, Shu-Yang[2] Guo, Peng[2]
机构:Capital Med Univ;Capital Med Univ;Capital Med Univ;Capital Med Univ;Capital Med Univ
来源:SCIENTIFIC REPORTS  
Identification of Differentially Expressed Genes in Pituitary Adenomas by Integrating Analysis of Microarray Data被引量:17收藏 分享
作者:Zhao, Peng[1] Hu, Wei[2] Wang, Hongyun[3] Yu, Shengyuan[3] Li, Chuzhong[3]
机构:Capital Med Univ;Beijing Chuiyangliu Hosp;Capital Med Univ
来源:INTERNATIONAL JOURNAL OF ENDOCRINOLOGY  
A comparative study of the amount of alpha-synuclein in ischemic stroke and Parkinson's disease被引量:17收藏 分享
作者:Zhao, Hui-Qing[1,2] Li, Fang-fei[1,2] Wang, Zhan[1,2] Wang, Xue-Mei[1,2] Feng, Tao[1,2,3]
机构:Capital Med Univ;China Natl Clin Res Ctr Neurol Dis;Capital Med Univ
来源:NEUROLOGICAL SCIENCES  
精神分裂症的预防与治疗被引量:17收藏 分享
作者:王传跃[1] 陈晓岗[2]
机构:首都医科大学附属北京安定医院精神疾病诊断与治疗北京市重点实验室/北京脑重大疾病研究院精神分裂症研究所;中南大学湘雅二医院精神卫生研究所
来源:《中华医学杂志》  
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肠道菌群与高血压被引量:16收藏 分享
作者:许杰[1] 王伊龙[1] 王拥军[1]
机构:首都医科大学附属北京天坛医院
来源:《中国卒中杂志》  
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Glycated albumin predicts the effect of dual and single antiplatelet therapy on recurrent stroke被引量:16收藏 分享
作者:Li, Jiejie[1] Wang, Yilong[1] Wang, David[2] Lin, Jinxi[1] Wang, Anxin[1]
机构:Capital Med Univ; Natl Clin Res Ctr Neurol Dis; Beijing Inst Brain Disorders;Univ Illinois
来源:NEUROLOGY  
Galanin Protects from Caspase-8/12-initiated Neuronal Apoptosis in the Ischemic Mouse Brain via GalR1被引量:16收藏 分享
作者:Li, Yun Mei, Zhu Liu, Shuiqiao Wang, Tong Li, Hui
机构:Capital Med Univ;Capital Med Univ
来源:AGING AND DISEASE  
9例原发性中枢神经系统血管炎临床、影像及病理特点研究被引量:16收藏 分享
作者:李伟[1] 李少武[2] 王晶[3] 张在强[1]
机构:首都医科大学附属北京天坛医院神经病学中心;首都医科大学附属神经外科研究所;首都医科大学遗传教研室
来源:《中国卒中杂志》  
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The clinicopathological features of pituicytoma and the differential diagnosis of sellar glioma被引量:16收藏 分享
作者:Wang, Junmei[1] Liu, Zhaoxia[1] Du, Jiang[1] Cui, Yun[1] Fang, Jingyi[1]
机构:Capital Med Univ
来源:NEUROPATHOLOGY  
自发性凸面蛛网膜下腔出血的临床和影像学特点被引量:16收藏 分享
作者:杜万良[1] 荆京[1] 王伊龙[1] 王拥军[1]
机构:首都医科大学附属北京天坛医院神经病学中心
来源:《中国卒中杂志》  
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Triptolide up-regulates metabotropic glutamate receptor 5 to inhibit microglia activation in the lipopolysaccharide-induced model of Parkinson's disease被引量:16收藏 分享
作者:Huang, Yi-Ying[1,2] Zhang, Qian[1,2] Zhang, Jian-Nan[1,2] Zhang, Ya-Nan[1,2] Gu, Li[1,2]
机构:Capital Med Univ;Capital Med Univ;Burke Med Res Inst
来源:BRAIN BEHAVIOR AND IMMUNITY  
Collapsin response mediator protein-2 plays a major protective role in acute axonal degeneration被引量:16收藏 分享
作者:Zhang, Jian-Nan[1,2,3] Koch, Jan C.[1,4]
机构:Univ Med Gottingen;Capital Med Univ;Capital Med Univ;Ctr Nanoscale Microscopy & Mol Physiol Brain CNMP
来源:NEURAL REGENERATION RESEARCH  
Aβ selectively impairs mGluR7 modulation of NMDA signaling in basal forebrain cholinergic neurons: Implication in alzheimer’s disease被引量:16收藏 分享
作者:Gu Z.[1] Cheng J.[1] Zhong P.[1,2] Qin L.[1] Liu W.[1]
机构:Department of Physiology and Biophysics;Veterans Administration Western New York Healthcare System;Department of Neurobiology
来源:Journal of Neuroscience  
A more consistent intraluminal rhesus monkey model of ischemic stroke被引量:15收藏 分享
作者:Zhao, Bo[1] Shang, Guowei[1] Chen, Jian[1] Geng, Xiaokun[1] Ye, Xin[2]
机构:Capital Med Univ;Capital Med Univ;Capital Med Univ;Capital Med Univ;Wayne State Univ
来源:NEURAL REGENERATION RESEARCH  
Pneumonia Can Cause Clozapine Intoxication: A Case Report被引量:15收藏 分享
作者:Ruan, Can-Jun[1] Zhen, Xue-Yang[2] Ge, Xin-Liang[2] Wang, Chuan-Yue[2] Guo, Wei[3]
机构:Capital Med Univ;Capital Med Univ;Capital Med Univ;Emory Univ;Eastern State Hosp
来源:PSYCHOSOMATICS  
ESR1 and its antagonist fulvestrant in pituitary adenomas被引量:15收藏 分享
作者:Gao, Hua[1] Xue, Yake[2] Cao, Lei[3] Liu, Qian[1] Liu, Chunhui[1]
机构:Capital Med Univ;Zhengzhou Univ;Beijing Tiantan Hosp
来源:MOLECULAR AND CELLULAR ENDOCRINOLOGY  
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